Publications

Selected publications

Brás MMF, Sousa SR, Carneiro F, Radmacher M, Granja PL. Mechanobiology of colorectal cancer. Cancers 2022;14:1945. DOI: https://doi.org/10.3390/cancers14081945.

Ferreira D, Rothbauer M, Conde JP, Ertl P, Oliveira C, Granja PL. A fast alternative to soft-lithography for the fabrication of organ-on-a-chip elastomeric-based devices and microactuators. Adv Sci 2021;2003273. DOI: https://doi.org/10.1002/advs.202003273.

Pereira RF, Lourenço BN, Bártolo PJ, Granja PL. Bioprinting a multifunctional bioink to engineer clickable 3D cellular niches with tunable matrix microenvironmental cues. Adv Healthc Mater 2021;10:2001176. DOI: https://doi.org/10.1002/adhm.202001176.

Lourenço BN, Pereira RF, Barrias CC, Fischbach C, Oliveira C, Granja PL. Engineering modular half-antibody conjugated nanoparticles for targeting CD44v6-expressing cancer cells. Nanomaterials 2021;11:295. DOI: https://doi.org/10.3390/nano11020295.

Bauleth‐Ramos T, Feijão T, Gonçalves A, Shahbazi M‐A, Liu Z, Barrias C, Oliveira MJ, Granja P, Santos HA, Sarmento B. Colorectal cancer triple co-culture spheroid model to assess the biocompatibility and anticancer properties of polymeric nanoparticles. J Control Release 2020;323:398-411. DOI: https://doi.org/10.1016/j.jconrel.2020.04.025.

Wang Z, Kapadia W, Li C, Lin F, Pereira RF, Granja PL, Sarmento B, Cui W. Tissue-specific engineering: 3D bioprinting in regenerative medicine. J Control Release 2021;329:237-56. DOI: https://doi.org/10.1016/j.jconrel.2020.11.044.

Neves SC, Moroni L, Barrias CC, Granja PL. Leveling up hydrogels: Hybrid systems in tissue engineering. Trends Biotechnol 2020;3:292-315. DOI: https://doi.org/10.1016/j.tibtech.2019.09.004.

Bauleth‐Ramos T, Shih T‐Y, Shahbazi M‐A, Najibi AJ, Ma AS, Liu, D, Granja P, Santos HA, Sarmento B, Mooney DJ. Acetalated dextran nanoparticles loaded into an injectable alginate cryogel for combined chemotherapy and cancer vaccination. Adv Funct Mater 2019;29:1903686. DOI: 10.1002/adfm.201703303.

Pereira RF, Sousa A, Barrias CC, Bártolo PJ, Granja PL. A single-component hydrogel bioink for bioprinting of bioengineered 3D constructs for dermal tissue engineering. Mater Horizons 2018;5:1100-11. DOI: 10.1039/c8mh00525g.

Lourenço BN, Dos Santos T, Oliveira C, Barrias CC, Granja PL. Bioengineering a novel 3D in vitro model of gastric mucosa for stomach permeability studies. Acta Biomater 2018;82:68-78.

Costa-Almeida R, Soares R, Granja PL. Fibroblasts as maestros orchestrating tissue regeneration. J Tissue Eng Regen Med 2018;12:240-51. DOI: 10.1002/term.2405.

Kennedy PJ, Oliveira C, Granja PL, Sarmento B. Monoclonal antibodies: Technologies for early discovery and engineering. Crit Rev Biotechnol 2018;38:394-408. DOI: https://doi.org/10.1080/07388551.2017.1357002.

Lourenço BN, Springer NL, Ferreira D, Oliveira C, Granja PL, Fischbach C. CD44v6 increases gastric cancer malignant phenotype by modulating adipose stromal cell-mediated ECM remodeling. Integr Biol 2018;10:145-58. DOI: 10.1039/c7ib00179g.

Pereira RF, Barrias CC, Bártolo PJ, Granja PL. Cell-instructive pectin hydrogels crosslinked via thiol-norbornene photo-click chemistry for skin tissue engineering. Acta Biomater 2018;66:282-93. https://doi.org/10.1016/j.actbio.2017.11.016.

Bauman E, Granja PL, Barrias CC. Fetal bovine serum‐free culture of endothelial progenitor cells-progress and challenges. J Tissue Eng Regen Med 2018;12:1567-78. DOI: 10.1002/term.2678.

Dias JR, Baptista-Silva S, Sousa A, Oliveira AL, Bártolo PJ, Granja PL. Biomechanical performance of hybrid electrospun structures for skin regeneration. Mat Sci Eng C Mater Biol Appl 2018;93:816-27. https://doi.org/10.1016/j.msec.2018.08.050.

Bauman E, Feijão T, Carvalho DTO, Granja PL, Barrias CC. Xeno-free pre-vascularized spheroids for therapeutic applications. Sci Rep 2018:8:230. DOI:10.1038/s41598-017-18431-6.

Kennedy PJ, Oliveira C, Granja PL, Sarmento B. Monoclonal antibodies: Technologies for early discovery and engineering. Crit Rev Biotechnol 2018;38:394-408. DOI: https://doi.org/10.1080/07388551.2017.1357002.

Dias JR, Baptista-Silva S, Sousa A, Oliveira AL, Bártolo PJ, Granja PL. Biomechanical performance of hybrid electrospun structures for skin regeneration. Mat Sci Eng C Mater Biol Appl 2018;93:816-27. https://doi.org/10.1016/j.msec.2018.08.050.

Neves MI, Wechsler ME, Gomes ME, Reis RL, Granja PL*, Peppas NA*. Molecularly imprinted intelligent scaffolds for tissue engineering applications. Tissue Eng B Rev  2017;23:27-43. *Equal contribution. DOI: 10.1089/ten.teb.2016.0202. 

Kennedy P, Oliveira C, Granja PL, Sarmento B. Antibodies and associates: Partners in targeted drug delivery. Pharmacol Ther 2017;177:129-45. DOI: http://dx.doi.org/10.1016/j.pharmthera.2017.03.004.

Araújo F, das Neves J, Martins JP, Granja PL, Santos HA, Sarmento B. Functionalized materials for multistage platforms in the oral delivery of biopharmaceuticals. Prog Mater Sci 2017;89:306-44. DOI: http://dx.doi.org/10.1016/j.pmatsci.2017.05.001.

Costa-Almeida R,* Carvalho DTO,* Ferreira MJS,* Aresta G,* Gomes ME, Van Loon JJWA, Van der Heiden K, Granja PL. Effects of hypergravity on the angiogenic potential of endothelial cells. J R Soc Interface 2016;13:20160688. *Equal contribution. DOI: http://dx.doi.org/10.1098/rsif.2016.0688.

Neves SC, Mota C, Longoni A, Barrias CC, Granja PL, Moroni L. Additive manufactured polymeric 3D scaffolds with tailored surface topography influence mesenchymal stromal cells activity. Biofabrication 2016;8:025012. DOI:10.1088/1758-5090/8/2/025012.

Branco da Cunha C, Klumpers DD, Koshy ST, Weaver JC, Chaudhuri O, Seruca R, Carneiro F, Granja PL, Mooney DJ. CD44 alternative splicing in gastric cancer cells is regulated by culture dimensionality. Biomaterials 2016;98:152-62. DOI: http://dx.doi.org/10.1016/j.biomaterials.2016.04.016.

Araújo F, Shrestha N, Gomes MJ, Liu D, Hirvonen J, Granja PL, Santos HA, Sarmento B. In vivodual-delivery of glucagon like peptide -1 (GLP-1) and dipeptidyl peptidase-4 (DPP4) inhibitor through composites prepared by microfluidics for diabetes therapy. Nanoscale 2016;8:10706-13. DOI: 10.1039/c6nr00294c (IF 7.367)

Dias J, Granja PL*, Bártolo PJ*. Advances in electrospun skin substitutes. Prog Mater Sci 2016;84:314-34. *Equal contribution. DOI: http://dx.doi.org/10.1016/j.pmatsci.2016.09.006. (IF 31.140)

Araújo F, Shrestha N, Shahbazi M-A, Liu D, Herranz-Blanco B, Mäkilä E, Salonen J, Hirvonen J, Granja PL, Sarmento B, Santos HA. Microfluidic assembly of a multimodal tailorable system designed for site specific combined oral delivery of peptide-drug. ACS Nano 2015;9:8291-302. DOI: 10.1021/acsnano.5b02762. (IF 13.334)

Pereira C, Araújo F, Barrias CC, Granja PL, Sarmento B. Dissecting stromal-epithelial interactions in a 3D in vitro cellularized intestinal model for permeability studies. Biomaterials 2015;56:36-45. DOI: http://dx.doi.org/10.1016/j.biomaterials.2015.03.054 (IF 8.387)

Neves SC, Gomes DB, Sousa A, Bidarra SJ, Petrini P, Moroni L, Barrias CC, Granja PL. Biofunctionalized pectin hydrogels as 3D cellular microenvironments. J Mater Chem B 2015;3:2096-108. DOI: 10.1039/c4tb00885e. (IF 4.872)

Costa-Almeida R, Granja PL, Gomes ME. Gravity, tissue engineering, and the missing link. Trends Biotechnol 2017; 36:343-7. DOI: https://doi.org/10.1016/j.tibtech.2018.02.003. (IF 13.578)

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